Mechanisms of Mitochondrial Damage in Keratinocytes by Pemphigus Vulgaris Antibodies
نویسندگان
چکیده
منابع مشابه
Mechanisms of mitochondrial damage in keratinocytes by pemphigus vulgaris antibodies.
The development of nonhormonal treatment of pemphigus vulgaris (PV) has been hampered by a lack of clear understanding of the mechanisms leading to keratinocyte (KC) detachment and death in pemphigus. In this study, we sought to identify changes in the vital mitochondrial functions in KCs treated with the sera from PV patients and healthy donors. PV sera significantly increased proton leakage f...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2013
ISSN: 0021-9258
DOI: 10.1074/jbc.m113.472100